NGT’s experts collaborate with a network of equipment manufacturers, engineering firms and innovative technology service providers to advise and tactically support the design and implementation of transformative manufacturing technology platforms and facilities:
CASE STUDY – Drug Manufacturing Innovation
A large pharmaceutical company sought to accelerate their product launch timelines for late-stage clinical small molecule drugs.
They wished to transition powder-to-tablet manufacturing processes used for Ph 1/2 clinical supplies to a continuous manufacturing platform to accommodate larger than originally projected commercial volumes. A modular continuous manufacturing concept capable of smaller production & rapid scale-up for future variable ‘on demand’ supply was required.
Conceptual design of a continuous tablet manufacturing line in an environmentally isolated POD was developed.
A business case was prepared and presented to company governance bodies to gather stakeholder alignment and secure financing.
A multi-party collaboration was established, and oversight of design and fabrication was provided by NGT in close collaboration with internal and external partners.
Reduced time and resource spend for the launch of a new facility was successfully achieved. The facility was ultimately commissioned to manufacture commercial supply of a recently approved drug while additional candidates in late clinical development are planned to be manufactured from this facility.
A second facility was built and commissioned at one of their European manufacturing sites.